Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639607 | 0.90 | KDM4E (0.49) | KDM4EHSD17B10PDE7AERCC5FEN1 | |
| SCHEMBL9641124 | 0.86 | KMT2A (0.43) | KDM4EHSD17B10KCNMA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9640865 | 0.82 | OR51E2 (0.47) | KDM4ESMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL9639889 | 0.81 | CYP1A2 (0.48) | KDM4EHSD17B10KCNMA1ALDH1A1MAPT | |
| SCHEMBL8752479 | 0.81 | CYP2C19 (0.53) | KDM4ESMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8211833 | 0.79 | KMT2A (0.49) | KDM4EHSD17B10KCNMA1ALDH1A1MAPT | |
| SCHEMBL7085464 | 0.79 | CYP2C19 (0.41) | KDM4EPDE7AERCC5FEN1SMN1; SMN2 | |
| SCHEMBL7091629 | 0.78 | CYP2C19 (0.38) | KDM4EHSD17B10PDE7AKCNMA1SMN1; SMN2 | |
| SCHEMBL7084865 | 0.78 | GAA (0.53) | KDM4ESMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL9469411 | 0.78 | KDM4E (0.77) | KDM4EHSD17B10KCNMA1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0339411-A1 | Process for the preparation of quinoxalones | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |