Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295850 | 0.90 | KMT2A (0.68) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL7551865 | 0.89 | HDAC1 (0.59) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL1738859 | 0.86 | FASN (0.68) | KMT2AMEN1HDAC1LMNAHPGD | |
| SCHEMBL30063117 | 0.84 | LMNA (0.66) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL170272 | 0.84 | LMNA (0.66) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL7046942 | 0.84 | KMT2A (0.70) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL28858093 | 0.83 | MEN1 (0.59) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL11757510 | 0.82 | HDAC1 (0.59) | KMT2AMEN1GAAHDAC1LMNA | |
| Exifone SCHEMBL18993025 | 0.81 | HDAC1 (0.80) | KMT2AMEN1USP2GAAKEAP1 | |
| Exifone SCHEMBL11756630 | 0.80 | HDAC1 (0.73) | KMT2AMEN1USP2GAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227487-B1 | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |