Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581279 | 0.90 | NPC1 (0.45) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL9756997 | 0.73 | LMNA (0.50) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL9756994 | 0.73 | LMNA (0.50) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL15758324 | 0.72 | NPC1 (0.54) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL4912952 | 0.72 | NFE2L2 (0.48) | NFE2L2 | |
| SCHEMBL15765203 | 0.72 | NPC1 (0.54) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL29940285 | 0.69 | CA12 (0.47) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL2882462 | 0.69 | CA12 (0.47) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL2882460 | 0.69 | CA12 (0.47) | NPC1L3MBTL1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL2641810 | 0.69 | SNCA (0.48) | NPC1NFE2L2LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5107057-A | Reacting protected 1,3-dialdehyde and a cyano-diene; halogenation, cyclization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-21 | — | — | US | disclosed |