Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351262 | 0.84 | LMNA (0.48) | KDM4EALDH1A1HPGDCA1CA2 | |
| SCHEMBL21667786 | 0.84 | CA4 (0.62) | KDM4EALDH1A1CA1CA2BACE1 | |
| SCHEMBL6320332 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDCES2CES1 | |
| SCHEMBL21667800 | 0.82 | CA4 (0.59) | KDM4EALDH1A1CA1CA2BACE1 | |
| SCHEMBL21667799 | 0.82 | CA4 (0.59) | KDM4EALDH1A1CA1CA2BACE1 | |
| SCHEMBL16672197 | 0.82 | CA4 (0.59) | KDM4EALDH1A1CA1CA2BACE1 | |
| Bicarbonate SCHEMBL28112150 | 0.81 | CES2 (0.61) | KDM4EALDH1A1CES2CES1CA1 | |
| SCHEMBL10405305 | 0.80 | LMNA (0.48) | KDM4EALDH1A1HPGDCA1CA2 | |
| SCHEMBL3668412 | 0.79 | ALDH1A1 (0.55) | GFERKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL29094128 | 0.78 | CDC25B (0.50) | ALDH1A1HPGDPOLBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175242-A | PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES | THE UNIVERSITY OF AKRON (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0499603-A1 | PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES | THE UNIVERSITY OF AKRON (US) | 1992-08-26 | — | — | EP | disclosed |
| WO-1990010025-A1 | PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES | THE UNIVERSITY OF AKRON (US) | 1990-09-07 | — | — | WO | disclosed |