Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.66 |
| ▸ | PLG | P00747 | 1/20 | 0.66 |
| ▸ | PLAT | P00750 | 1/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620321 | 0.90 | CYP1A2 (0.66) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL23367928 | 0.89 | RAB9A (0.75) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL21652225 | 0.87 | KCNK9 (0.68) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL14082970 | 0.83 | PLAU (0.57) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL23367931 | 0.82 | CYP1A2 (0.78) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL5182427 | 0.82 | NPC1 (0.61) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL2093226 | 0.81 | CA2 (0.58) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10055020 | 0.81 | NPC1 (0.94) | KMT2ANPC1RAB9ATP53PKM | |
| SCHEMBL2093222 | 0.81 | CA2 (0.58) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL17680726 | 0.81 | CA2 (0.58) | PLAUF2PLGPLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282266-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID AMIDES OR ESTERS | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |