Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640383 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA9CHRM2CHRM1 | |
| SCHEMBL85690 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL9506330 | 0.71 | — | — | |
| SCHEMBL9639468 | 0.71 | — | — | |
| SCHEMBL13028429 | 0.70 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL785945 | 0.69 | MEN1 (0.33) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL14593908 | 0.68 | HTT (0.33) | SMN1; SMN2 | |
| SCHEMBL786154 | 0.68 | CHRM2 (0.32) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL11965866 | 0.66 | CHRM1 (0.36) | CHRM1F2R | |
| SCHEMBL5521244 | 0.65 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA9CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106870-A | Antiinflammatory agents, antianaphylactic agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | disclosed |
| US-4992581-A | From perhydroketo-4,7-methanoindene | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-02-12 | — | — | US | disclosed |
| US-4973604-A | Thromboxane A2 antagonists and pharmaceutical compositions thereof | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-11-27 | — | — | US | disclosed |
| US-4942256-A | 7-(3-ALPHA-(1-(((PHENYLAMINO)-THIOXOMETHYL)HYDRAZINO)ETHYL)-BI CYCLO(2.2.1)HEPTENOIC ACIDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-07-17 | — | — | US | disclosed |
| WO-1990006917-A1 | NOVEL THROMBOXANE A2 ANTAGONISTS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-06-28 | — | — | WO | disclosed |
| EP-0373915-A1 | Novel thromboxane A2 antagonists | BTG INTERNATIONAL LIMITED (GB) | 1990-06-20 | — | — | EP | disclosed |