Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.52 |
| ▸ | HTR3B | O95264 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 3/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9639371 | 0.94 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9640631 | 0.85 | PARP1 (0.53) | HSD11B1PARP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22597980 | 0.83 | HTR3E (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Propionic Acid SCHEMBL9640910 | 0.81 | PARP1 (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Butyric Acid SCHEMBL9640083 | 0.81 | PARP1 (0.50) | PARP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9036589 | 0.81 | SIGMAR1 (0.51) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9036531 | 0.80 | PPARG (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8795094 | 0.79 | HSD11B1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9037849 | 0.78 | PPARG (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9755222 | 0.78 | PARP1 (0.52) | HTR1AHTR2CHSD11B1PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496746-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1992-08-05 | — | — | EP | disclosed |