Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 6/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937807 | 0.83 | MAPK1 (0.44) | MAPK1GBA1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL22129037 | 0.80 | MAPK1 (0.41) | MAPK1SIGMAR1ALDH1A1 | |
| SCHEMBL12178201 | 0.77 | — | — | |
| SCHEMBL4084781 | 0.77 | OPRM1 (0.33) | MAPK1 | |
| SCHEMBL12371257 | 0.77 | OPRM1 (0.33) | MAPK1 | |
| SCHEMBL14258660 | 0.76 | GBA1 (0.49) | GBA1SIGMAR1ALDH1A1GLB1 | |
| SCHEMBL1920518 | 0.74 | MAPK1 (0.42) | MAPK1GBA1KDM4EALDH1A1KMT2A | |
| SCHEMBL2353862 | 0.74 | MAPK1 (0.39) | MAPK1GBA1KMT2A | |
| SCHEMBL8267457 | 0.74 | CNR1 (0.34) | MAPK1 | |
| SCHEMBL8237729 | 0.73 | LTA4H (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128408-A | Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1992-07-07 | — | — | US | disclosed |