Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640469 | 0.93 | THRB (0.42) | THRBLMNASMN1; SMN2PTPN7THRA | |
| SCHEMBL9750971 | 0.90 | PTPN7 (0.48) | THRBSMN1; SMN2PTPN7THRAPPARD | |
| SCHEMBL9640056 | 0.87 | PLA2G7 (0.34) | THRBTLR7PLA2G7LMNASMN1; SMN2 | |
| SCHEMBL9639586 | 0.84 | PLA2G7 (0.39) | THRBPLA2G7LMNATHRAMRGPRX4 | |
| SCHEMBL9750878 | 0.83 | PTPN7 (0.52) | THRBSMN1; SMN2PTPN7THRAPPARD | |
| SCHEMBL9644988 | 0.80 | MEN1 (0.39) | THRBTLR7LMNASMN1; SMN2THRA | |
| SCHEMBL10441387 | 0.80 | TLR7 (0.35) | THRBTLR7PLA2G7THRAMEN1 | |
| SCHEMBL9634929 | 0.80 | RAB9A (0.41) | THRBTLR7THRAMEN1KMT2A | |
| SCHEMBL9750855 | 0.79 | KMT2A (0.40) | THRBTLR7PLA2G7LMNATHRA | |
| SCHEMBL9489900 | 0.79 | FFAR1 (0.44) | THRBTLR7LMNASMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361067-B1 | DISUBSTITUTED NAPHTHALINES, PREPARATION PROCESSES AND THEIR HERBICIDAL USE | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-5108489-A | HERBICIDAL DISUBSTITUTED NAPHTHALENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0361067-A1 | Disubstituted naphthalines, preparation processes and their herbicidal use | BAYER AG (DE) | 1990-04-04 | — | — | EP | disclosed |