Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641613 | 0.94 | BCL2 (0.47) | BCL2PRKACAAKT1AKT2AKT3 | |
| SCHEMBL9640737 | 0.84 | CHRM3 (0.41) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL9642016 | 0.83 | CHRM3 (0.43) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL9281271 | 0.76 | MAPT (0.38) | RPS6KB1HTTPOLBLMNA | |
| SCHEMBL9640768 | 0.74 | CCR2 (0.35) | KMT2AMEN1LMNA | |
| SCHEMBL224352 | 0.74 | DAO (0.41) | HTTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL9092179 | 0.73 | OPRM1 (0.39) | RPS6KB1HTTPOLBSMN1; SMN2LMNA | |
| SCHEMBL9641967 | 0.71 | CHRM3 (0.34) | — | |
| SCHEMBL9641145 | 0.70 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1300384 | 0.70 | NPC1 (0.52) | KMT2AMEN1TSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311447-B1 | AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1992-08-26 | — | — | EP | claimed |
| EP-0311447-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1989-04-12 | — | — | EP | claimed |
| EP-0311447-B1 | AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1992-08-26 | — | — | EP | disclosed |
| US-5098923-A | Antiestrogens, anticarcinogenic agents or fungicides | FARMOS-YHTYMA OY (FI) | 1992-03-24 | — | — | US | disclosed |
| EP-0311447-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1989-04-12 | — | — | EP | disclosed |