Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640788 | 1.00 | MAPK1 (0.41) | MAPK1TP53NFKB1CYP2C19THPO | |
| Fluoride SCHEMBL10972490 | 0.97 | MAPK1 (0.39) | MAPK1TP53NFKB1CYP2C19THPO | |
| Hydrochloric Acid SCHEMBL9639877 | 0.97 | MAPK1 (0.39) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL9639872 | 0.78 | — | — | |
| SCHEMBL1376057 | 0.77 | MAPK1 (0.44) | MAPK1TP53NFKB1CYP2C19THPO | |
| Bicarbonate SCHEMBL9628771 | 0.77 | MAPK1 (0.33) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL10972489 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL11238901 | 0.74 | MAPK1 (0.42) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL9628774 | 0.74 | APLNR (0.31) | — | |
| SCHEMBL9869858 | 0.74 | MAPK1 (0.34) | MAPK1TP53NFKB1CYP2C19THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117053-A | Intermediate for | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5061731-A | Agricultural; horticultural | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4710518-A | Novel N-benzyl-cyclopropanecarboxamide fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-12-01 | — | — | US | disclosed |