SCHEMBL9628774

SCHEMBL9628774

CC1C(C)(C)C1(Cl)Cl.O=C(O)Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9628771 0.91 MAPK1 (0.33) APLNR
SCHEMBL10604385 0.82 APLNR (0.31) APLNR
SCHEMBL8959112 0.80
SCHEMBL9639872 0.74
SCHEMBL9640788 0.74 MAPK1 (0.41)
SCHEMBL9640786 0.74 MAPK1 (0.41)
SCHEMBL1930203 0.74 MAPK1 (0.36)
Bicarbonate SCHEMBL10606382 0.73 MAPK1 (0.33) APLNR
Hydrochloric Acid SCHEMBL9639877 0.72 MAPK1 (0.39)
Fluoride SCHEMBL10972490 0.72 MAPK1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257448-B1 OPTICALLY ACTIVE CYCLOPROPANECARBOXAMIDES NIHON BAYER AGROCHEM K.K. (JP) 1992-03-11 EP disclosed
EP-0257448-A2 Optically active cyclopropanecarboxamides NIHON BAYER AGROCHEM K.K. (JP) 1988-03-02 EP disclosed