Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641124 | 0.81 | KMT2A (0.43) | KMT2AMEN1PKMKCNMA1NPSR1 | |
| SCHEMBL9640825 | 0.81 | KDM4E (0.61) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL9640865 | 0.78 | OR51E2 (0.47) | CYP1A2CYP2C19KMT2AMEN1PKM | |
| SCHEMBL3885198 | 0.78 | KDM4E (0.59) | CYP1A2CYP2C9CYP2C19RXFP1ALDH1A1 | |
| SCHEMBL16739563 | 0.77 | KCNMA1 (0.63) | KMT2AMEN1PKMTHRBKCNMA1 | |
| SCHEMBL8752479 | 0.76 | CYP2C19 (0.53) | CYP1A2CYP2C9CYP2C19PKMCYP3A4 | |
| SCHEMBL12894745 | 0.75 | CFTR (0.57) | CYP1A2CYP2C9CYP2C19RXFP1KMT2A | |
| SCHEMBL9639607 | 0.75 | KDM4E (0.49) | KMT2AMEN1NPSR1ALDH1A1POLB | |
| SCHEMBL7088769 | 0.74 | CYP2C19 (0.34) | CYP2C19RXFP1KMT2AMEN1KCNMA1 | |
| SCHEMBL22057590 | 0.73 | ALDH1A1 (0.59) | CYP1A2CYP2C9CYP2C19RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |