Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907067 | 0.84 | PDE4A (0.44) | PDE4AKDM4EMAPK1NSD2CTSV | |
| SCHEMBL9639451 | 0.82 | NPSR1 (0.46) | KMT2AMEN1TSHRHTTGLA | |
| SCHEMBL4416389 | 0.78 | ACHE (0.43) | PDE4AALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL11165353 | 0.77 | MAPK8 (0.39) | HTTPDE4AKDM4EMAPK1LMNA | |
| SCHEMBL4909704 | 0.77 | ADORA2B (0.44) | KMT2AMEN1TSHRHTTGLA | |
| Pyridine SCHEMBL4898097 | 0.73 | ACHE (0.40) | KMT2AMEN1TSHRPDE4ASMN1; SMN2 | |
| SCHEMBL9640969 | 0.72 | KMT2A (0.53) | KMT2AMEN1TSHRHTTGLA | |
| SCHEMBL11174566 | 0.71 | HTT (0.41) | HTTPDE4AALDH1A1KDM4EMAPK1 | |
| SCHEMBL4907249 | 0.71 | KMT2A (0.41) | KMT2AMEN1PDE4AALDH1A1HPGD | |
| SCHEMBL4906201 | 0.71 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0273862-B1 | NON-AQUEOUS LIQUID ECTOPARASITICIDAL POUR-ON FORMULATION | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0273862-A2 | Non-aqueous liquid ectoparasiticidal pour-on formulation | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |