Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120066 | 0.84 | CTSK (0.38) | NPSR1MEN1KMT2AMAPTKDM4E | |
| Water SCHEMBL6817641 | 0.84 | CTSK (0.38) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9640912 | 0.82 | KMT2A (0.45) | NPSR1MEN1KMT2AMAPTKDM4E | |
| Cyromazine SCHEMBL5742773 | 0.78 | CCNA2 (0.39) | MEN1KMT2AACHE | |
| SCHEMBL27847094 | 0.74 | MAPK8 (0.39) | NPSR1KMT2AMAPTKDM4EHTT | |
| SCHEMBL9812684 | 0.71 | ALOX15 (0.36) | MAPTKDM4EHTTLMNAMAPK1 | |
| SCHEMBL21933409 | 0.70 | CTSK (0.36) | — | |
| SCHEMBL8986160 | 0.69 | MEN1 (0.60) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10272163 | 0.69 | GAA (0.56) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4907067 | 0.67 | PDE4A (0.44) | KDM4EMAPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102399193-A | Preparation method of 4, 6-diamino-2-cyclopropylamino-5-cyanopyrimidine | LIANYUNGANG YAHUI MEDICAL CHEMICAL CO LTD | 2012-04-04 | — | — | CN | disclosed |
| CN-102250017-A | Synthesizing method of dicyclanil | Yangzhou tianhe pharmaceutical co ltd | 2011-11-23 | — | — | CN | disclosed |
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0273862-B1 | NON-AQUEOUS LIQUID ECTOPARASITICIDAL POUR-ON FORMULATION | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0273862-A2 | Non-aqueous liquid ectoparasiticidal pour-on formulation | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |
| CN-87103168-A | The pyrimidines that replaces | — | 1987-12-16 | — | — | CN | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |