Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.69 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642301 | 0.84 | CYP11B1 (0.77) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9642312 | 0.82 | CYP11B1 (1.00) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9092547 | 0.80 | CYP11B1 (0.73) | CYP11B1CYP11B2IDO1HSD11B1 | |
| SCHEMBL9123088 | 0.78 | CYP11B1 (0.67) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL250955 | 0.77 | TDP1 (0.68) | PKMSMN1; SMN2CASP1TDP1NPSR1 | |
| SCHEMBL9092259 | 0.76 | CYP11B1 (0.68) | CYP11B1CYP11B2TDP1IDO1HSD11B1 | |
| SCHEMBL9092962 | 0.75 | CYP11B1 (0.72) | CYP11B1CYP11B2SMN1; SMN2IDO1 | |
| SCHEMBL6774918 | 0.72 | CYP11B1 (0.82) | CYP11B1CYP11B2TDP1IDO1 | |
| SCHEMBL9570444 | 0.72 | CYP11B1 (0.68) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL11221097 | 0.72 | TBXAS1 (0.49) | PKMSMN1; SMN2CASP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311447-B1 | AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1992-08-26 | — | — | EP | disclosed |
| US-5098923-A | Antiestrogens, anticarcinogenic agents or fungicides | FARMOS-YHTYMA OY (FI) | 1992-03-24 | — | — | US | disclosed |
| EP-0311447-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1989-04-12 | — | — | EP | disclosed |