Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.67 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642301 | 0.93 | CYP11B1 (0.77) | CYP11B1CYP11B2TBXAS1ALOX5MEN1 | |
| SCHEMBL6776094 | 0.85 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9092962 | 0.83 | CYP11B1 (0.72) | CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL2531890 | 0.82 | CYP11B1 (0.52) | CYP11B1CYP11B2TBXAS1ALOX5MEN1 | |
| SCHEMBL9642312 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9092547 | 0.78 | CYP11B1 (0.73) | CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL9642002 | 0.78 | CYP11B1 (0.69) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL260297 | 0.76 | ALOX5 (0.76) | ALOX5KMT2AFAAHCYP4F2CYP4A11 | |
| SCHEMBL27306308 | 0.75 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL9092259 | 0.75 | CYP11B1 (0.68) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439928-A | Enzyme inhibitors as antitumor agents for breast cancer | ORION-YHTYMA OY (FI) | 1995-08-08 | — | — | US | disclosed |
| EP-0390558-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-09-07 | — | — | EP | disclosed |
| CN-1068819-A | New selectivity aromatics enzyme suppresses 4 (5)-imidazoles | ORION YHTYMAE OY (FI) | 1993-02-10 | — | — | CN | disclosed |
| EP-0390558-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1990-10-03 | — | — | EP | disclosed |