Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235930 | 0.74 | PDPK1 (0.38) | LMNAALDH1A1CYP3A4OPRL1 | |
| SCHEMBL9439377 | 0.70 | MAOA (0.48) | LMNAALDH1A1OPRL1 | |
| SCHEMBL629665 | 0.69 | LMNA (0.36) | LMNAALDH1A1CYP3A4OPRL1 | |
| SCHEMBL9641668 | 0.69 | LMNA (0.32) | LMNAALDH1A1CYP3A4 | |
| SCHEMBL9642567 | 0.69 | LMNA (0.32) | LMNAALDH1A1CYP3A4 | |
| SCHEMBL18102902 | 0.68 | LMNA (0.38) | LMNAALDH1A1OPRL1 | |
| SCHEMBL20226481 | 0.68 | LMNA (0.38) | LMNAALDH1A1OPRL1 | |
| SCHEMBL20234219 | 0.68 | LMNA (0.38) | LMNAALDH1A1OPRL1 | |
| SCHEMBL9439491 | 0.68 | ALDH1A1 (0.39) | LMNAALDH1A1OPRL1 | |
| SCHEMBL22034479 | 0.66 | SLC5A2 (0.38) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275431-B1 | NOVEL ANTHRACYCLINE DERIVATIVES, A PROCESS FOR PREPARING SAME AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0275431-A1 | Novel anthracycline derivatives, a process for preparing same and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-07-27 | — | — | EP | disclosed |
| EP-0230322-A2 | 2,6-Dideoxy-2-fluoro-L-talopyranose and derivates thereof and the production of these compounds | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-07-29 | — | — | EP | disclosed |
| EP-0230013-A1 | New anthracycline derivatives, uses thereof as antitumor agent and production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1987-07-29 | — | — | EP | disclosed |