Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991465 | 0.79 | ALDH1A1 (0.41) | MAPTCYP1A2CYP2C19PARP1PARP10 | |
| SCHEMBL7275367 | 0.79 | MAPT (0.35) | KMT2AMAPTGAANPSR1CA9 | |
| SCHEMBL23426467 | 0.76 | FABP6 (0.40) | FABP6KMT2A | |
| SCHEMBL29358961 | 0.73 | GAA (0.60) | KMT2AMAPTPARP1GAANPSR1 | |
| SCHEMBL323313 | 0.73 | GAA (0.60) | KMT2AMAPTPARP1GAANPSR1 | |
| SCHEMBL9642426 | 0.72 | — | — | |
| SCHEMBL38662859 | 0.70 | ALOX5 (0.46) | KMT2AMAPTCYP1A2CYP2C19CA12 | |
| SCHEMBL17086925 | 0.70 | ALOX5 (0.46) | KMT2AMAPTCYP1A2CYP2C19CA12 | |
| SCHEMBL15763904 | 0.69 | FABP6 (0.39) | FABP6MAOBCA12CA2CA9 | |
| SCHEMBL22394766 | 0.69 | AHR (0.42) | KMT2AMAPTCYP1A2PARP1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108483-A | HERBICIDAL 6-HETEROCYCLIC GROUP SUBSTITUTED BENZOXAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0427031-A2 | N-aryl-nitrogen heterocycles | BAYER AG (DE) | 1991-05-15 | — | — | EP | disclosed |