Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lonapalene SCHEMBL120134 | 0.83 | ABCB11 (1.00) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9642993 | 0.83 | ABCB11 (0.53) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9641627 | 0.83 | ABCB11 (0.53) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9641821 | 0.83 | ABCB11 (0.54) | ABCB11PTGER1DHODHADORA3 | |
| SCHEMBL9643097 | 0.83 | ABCB11 (0.54) | ABCB11PTGER1DHODH | |
| SCHEMBL9643105 | 0.83 | ABCB11 (0.54) | ABCB11PTGER1DHODHADORA3 | |
| SCHEMBL9641815 | 0.83 | ABCB11 (0.54) | ABCB11PTGER1DHODH | |
| SCHEMBL9641851 | 0.82 | ABCB11 (0.97) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9642681 | 0.82 | ABCB11 (0.97) | ABCB11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9642961 | 0.80 | ABCB11 (0.76) | ABCB11PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |