Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642515 | 0.96 | ABCB11 (0.50) | ABCB11SMN1; SMN2ANO1ANO2MEN1 | |
| SCHEMBL9641690 | 0.93 | ABCB11 (0.58) | ABCB11SMN1; SMN2ANO1ANO2MEN1 | |
| SCHEMBL9643531 | 0.88 | ABCB11 (0.52) | ABCB11SMN1; SMN2ANO1ANO2MEN1 | |
| SCHEMBL9644109 | 0.88 | ABCB11 (0.52) | ABCB11SMN1; SMN2ANO1ANO2MEN1 | |
| SCHEMBL9642749 | 0.85 | ABCB11 (0.53) | ABCB11SMN1; SMN2LMNAL3MBTL1MAPT | |
| SCHEMBL9641822 | 0.83 | ABCB11 (0.46) | ABCB11SMN1; SMN2ANO1ANO2L3MBTL1 | |
| SCHEMBL9643258 | 0.82 | ABCB11 (0.46) | ABCB11SMN1; SMN2ANO1ANO2MEN1 | |
| SCHEMBL9643263 | 0.81 | ABCB11 (0.45) | ABCB11SMN1; SMN2ANO1ANO2L3MBTL1 | |
| SCHEMBL9642650 | 0.81 | ABCB11 (0.59) | ABCB11MEN1KMT2ALMNAGAA | |
| SCHEMBL9642952 | 0.81 | ABCB11 (0.53) | ABCB11SMN1; SMN2LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |