Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641690 | 0.87 | ABCB11 (0.58) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9641822 | 0.85 | ABCB11 (0.46) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9643531 | 0.82 | ABCB11 (0.52) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9644109 | 0.82 | ABCB11 (0.52) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9643258 | 0.82 | ABCB11 (0.46) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9643254 | 0.81 | ABCB11 (0.51) | ABCB11PDE4DALOX15PTGS2 | |
| SCHEMBL9643186 | 0.81 | ABCB11 (0.50) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9642515 | 0.81 | ABCB11 (0.50) | ABCB11ANO1ANO2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9643275 | 0.80 | ABCB11 (0.45) | ABCB11PLA2G4A | |
| SCHEMBL9643164 | 0.75 | ABCB11 (0.62) | ABCB11SMN1; SMN2L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |