Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641690 | 0.88 | ABCB11 (0.58) | ABCB11PPARGPPARAL3MBTL1ANO1 | |
| SCHEMBL9643531 | 0.83 | ABCB11 (0.52) | ABCB11PPARGPPARAL3MBTL1ANO1 | |
| SCHEMBL9644109 | 0.83 | ABCB11 (0.52) | ABCB11PPARGPPARAL3MBTL1ANO1 | |
| SCHEMBL9643263 | 0.82 | ABCB11 (0.45) | ABCB11L3MBTL1ANO1ANO2SMN1; SMN2 | |
| SCHEMBL9643186 | 0.82 | ABCB11 (0.50) | ABCB11PPARGPPARAL3MBTL1ANO1 | |
| SCHEMBL9642515 | 0.82 | ABCB11 (0.50) | ABCB11PPARGPPARAL3MBTL1ANO1 | |
| SCHEMBL9641822 | 0.80 | ABCB11 (0.46) | ABCB11L3MBTL1ANO1ANO2MAPT | |
| SCHEMBL9643246 | 0.79 | ABCB11 (0.50) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9643164 | 0.73 | ABCB11 (0.62) | ABCB11L3MBTL1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL9643005 | 0.71 | ABCB11 (0.44) | ABCB11MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |