Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 7/20 | 0.40 |
| ▸ | HAT1 | O14929 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641702 | 0.85 | ABCB11 (0.60) | ABCB11 | |
| SCHEMBL9643263 | 0.80 | ABCB11 (0.45) | ABCB11PLA2G4A | |
| SCHEMBL9643541 | 0.79 | ABCB11 (0.51) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9644111 | 0.79 | ABCB11 (0.51) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9643198 | 0.79 | ABCB11 (0.52) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9642523 | 0.79 | ABCB11 (0.52) | ABCB11 | |
| SCHEMBL9643254 | 0.73 | ABCB11 (0.51) | ABCB11 | |
| SCHEMBL9642160 | 0.71 | ABCB11 (0.70) | ABCB11 | |
| SCHEMBL9643850 | 0.71 | MAPT (0.41) | ABCB11 | |
| SCHEMBL9643344 | 0.71 | ABCB11 (0.59) | ABCB11PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |