Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953855 | 1.00 | SIGMAR1 (0.65) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9493476 | 0.91 | SIGMAR1 (0.67) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9492767 | 0.91 | SIGMAR1 (0.73) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9643179 | 0.83 | OPRK1 (0.82) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7962880 | 0.83 | OPRK1 (0.82) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL9772473 | 0.83 | OPRK1 (0.81) | SIGMAR1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9813887 | 0.83 | OPRK1 (0.82) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7963740 | 0.83 | OPRK1 (0.81) | SIGMAR1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL7077496 | 0.83 | OPRK1 (0.82) | SIGMAR1OPRM1OPRD1OPRK1 | |
| 1,2-Dichlorobenzene SCHEMBL9643149 | 0.82 | SIGMAR1 (0.59) | SIGMAR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258096-B1 | INDANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE INTERMEDIATES OBTAINED | ROUSSEL-UCLAF (FR) | 1992-09-09 | — | — | EP | claimed |
| US-5043347-A | Indanes and analgesic compositions and methods thereof | ROUSSEL UCLAF (FR) | 1991-08-27 | — | — | US | disclosed |