Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642595 | 1.00 | TK1 (0.61) | TK1 | |
| SCHEMBL9644049 | 0.90 | — | — | |
| SCHEMBL9642570 | 0.90 | — | — | |
| SCHEMBL9642633 | 0.89 | — | — | |
| SCHEMBL9780790 | 0.85 | — | — | |
| SCHEMBL9780802 | 0.85 | — | — | |
| SCHEMBL8845478 | 0.85 | TK1 (0.65) | TK1 | |
| SCHEMBL8845484 | 0.85 | TK1 (0.65) | TK1 | |
| SCHEMBL9780812 | 0.83 | — | — | |
| SCHEMBL8655891 | 0.83 | DUT (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256400-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-23 | — | — | EP | claimed |
| US-4886785-A | VIRICIDES, HERPES SIMPLEX | HOFFMANN-LA ROCHE INC. (US) | 1989-12-12 | — | — | US | claimed |
| US-4956346-A | URIDINE DERIVATIVES AS VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4886785-A | VIRICIDES, HERPES SIMPLEX | HOFFMANN-LA ROCHE INC. (US) | 1989-12-12 | — | — | US | disclosed |