Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922453 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1CTSLSMN1; SMN2 | |
| SCHEMBL9345773 | 0.81 | KMT2A (0.42) | ALDH1A1KMT2AMEN1CTSLTP53 | |
| SCHEMBL10921927 | 0.79 | CYP1A2 (0.48) | ALDH1A1KMT2AMEN1CTSLSMN1; SMN2 | |
| SCHEMBL10924508 | 0.79 | POLB (0.40) | ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL10410589 | 0.77 | LMNA (0.41) | ALDH1A1KMT2AMEN1TP53SMN1; SMN2 | |
| SCHEMBL9645999 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1TP53SMN1; SMN2 | |
| SCHEMBL10719844 | 0.76 | HDAC1 (0.47) | ALDH1A1KMT2AMEN1TP53SMN1; SMN2 | |
| SCHEMBL10412346 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1TP53SMN1; SMN2 | |
| SCHEMBL9533252 | 0.74 | HTT (0.35) | ALDH1A1KMT2AMEN1CTSLTP53 | |
| SCHEMBL10929658 | 0.74 | HDAC8 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104886-A | Syntergistic mixtures of amide substituted thiazoles and other fungicides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0313091-A2 | Amide derivatives, processes for production thereof, and agricultural-horticultural fungicide containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-26 | — | — | EP | disclosed |
| US-4792565-A | Pyrazolecarbonylamine derivatives and agricultural and horticultural fungicides containing said compounds | MITSUI TOATSU CHEMICALS, INC. (JP) | 1988-12-20 | — | — | US | disclosed |