Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921927 | 0.79 | CYP1A2 (0.48) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10665838 | 0.78 | CTSV (0.46) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9786414 | 0.78 | LMNA (0.34) | HTTALOX5SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8799757 | 0.76 | LMNA (0.51) | HTTSMN1; SMN2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9530946 | 0.76 | MME (0.36) | HTTALOX5SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9528349 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9644142 | 0.74 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL9345773 | 0.73 | KMT2A (0.42) | HTTALOX5SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10653073 | 0.73 | ALDH1A1 (0.41) | ALOX5ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL10922453 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313091-B1 | AMIDE DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF, AND AGRICULTURAL-HORTICULTURAL FUNGICIDE CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5104886-A | Syntergistic mixtures of amide substituted thiazoles and other fungicides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4980363-A | CONTROLLING PLANT DISEASES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0313091-A2 | Amide derivatives, processes for production thereof, and agricultural-horticultural fungicide containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-26 | — | — | EP | disclosed |