Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644467 | 1.00 | FAAH (0.47) | FAAHKMT2AMEN1MAPK1PLA2G10 | |
| SCHEMBL16566059 | 0.77 | FAAH (0.59) | FAAHKMT2AMEN1MAPK1PLA2G10 | |
| SCHEMBL6672418 | 0.77 | GLO1 (0.37) | — | |
| SCHEMBL6672423 | 0.77 | GLO1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6673610 | 0.76 | GLO1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6673606 | 0.76 | GLO1 (0.36) | — | |
| SCHEMBL6670901 | 0.74 | CTSK (0.46) | — | |
| SCHEMBL23834071 | 0.74 | KMT2A (0.60) | FAAHKMT2AMEN1MAPK1PLA2G10 | |
| SCHEMBL23834069 | 0.74 | KMT2A (0.60) | FAAHKMT2AMEN1MAPK1PLA2G10 | |
| SCHEMBL7151948 | 0.73 | KMT2A (0.54) | FAAHKMT2AMEN1MAPK1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505467-A1 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | Astra Pharmaceuticals Limited (GB) | 1992-09-30 | — | — | EP | claimed |
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | claimed |