Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553783 | 0.92 | HTR4 (0.65) | HTR4DRD2 | |
| SCHEMBL9645517 | 0.92 | HTR4 (0.73) | HTR4DRD2 | |
| SCHEMBL11456465 | 0.92 | HTR4 (0.70) | HTR4DRD2 | |
| SCHEMBL11397386 | 0.89 | DRD4 (0.72) | HTR4 | |
| SCHEMBL11002126 | 0.89 | HTR4 (0.74) | HTR4DRD2 | |
| SCHEMBL11457053 | 0.86 | HTR4 (0.69) | HTR4DRD2 | |
| SCHEMBL9644709 | 0.85 | DRD4 (0.67) | HTR4 | |
| Fumaric Acid SCHEMBL11580335 | 0.84 | DRD4 (0.65) | HTR4DRD2 | |
| Fumaric Acid SCHEMBL11580339 | 0.84 | DRD4 (0.65) | HTR4DRD2 | |
| SCHEMBL8722682 | 0.81 | HTR4 (1.00) | HTR4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327335-B1 | ARYLAMIDO(AND ARYLTHIOAMIDO)-AZABICYCLOALKANES FOR ENHANCING MEMORY OR CORRECTING MEMORY DEFICIENCY | SYNTHELABO (FR) | 1992-10-14 | — | — | EP | disclosed |
| US-4863919-A | Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0327335-A1 | Arylamido(and arylthioamido)-azabicycloalkanes for enhancing memory or correcting memory deficiency | SYNTHELABO (FR) | 1989-08-09 | — | — | EP | disclosed |
| EP-0190920-A2 | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes | SYNTHELABO (FR) | 1986-08-13 | — | — | EP | disclosed |
| US-4605652-A | ALZHEIMER'S DISEASE; SENILITY | A. H. ROBINS COMPANY, INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4213983-A | Treating gastro-intestinal disorders and emesis with n-(heterocyclic substituted) benzamides | BEECHAM GROUP LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |