Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274584 | 0.94 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL28993061 | 0.88 | TSHR (0.48) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL13329475 | 0.88 | TSHR (0.48) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL30449085 | 0.82 | L3MBTL1 (0.39) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL4570489 | 0.81 | CYP1A2 (0.48) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL3409801 | 0.81 | LMNA (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL16134218 | 0.79 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL27409888 | 0.79 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL13707524 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8432394 | 0.77 | TSHR (0.64) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622947-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| EP-0296580-B1 | PHENYLENE, FURYL, AND THIENYL LEUKOTRIENE B4 ANALOGUES | G.D. Searle & Co. (US) | 1992-11-11 | — | — | EP | disclosed |
| US-4895869-A | ANTIINFLAMMATORY | C. D. SEARLE & CO. (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0296580-A2 | Phenylene, furyl, and thienyl leukotriene B4 analogues | G.D. Searle & Co. (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4791133-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1988-12-13 | — | — | US | disclosed |