Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173661 | 0.88 | DGKA (0.53) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL9938326 | 0.83 | DGKA (0.48) | DGKATHRBLMNAPAMMAPT | |
| SCHEMBL27427969 | 0.83 | DGKA (0.45) | DNM1DGKATHRBLMNAPAM | |
| SCHEMBL27316330 | 0.83 | DGKA (0.45) | DGKATHRBLMNAMAPTTSHR | |
| SCHEMBL9164192 | 0.80 | CES2 (0.47) | DGKATHRBLMNAPAMMAPT | |
| SCHEMBL4447497 | 0.79 | NAAA (0.50) | DNM1DGKATHRBLMNAMAPT | |
| SCHEMBL8368772 | 0.79 | NAAA (0.50) | DNM1DGKATHRBLMNAMAPT | |
| SCHEMBL1994867 | 0.79 | NAAA (0.50) | DNM1DGKATHRBLMNAMAPT | |
| SCHEMBL1992481 | 0.79 | NAAA (0.50) | DNM1DGKATHRBLMNAMAPT | |
| SCHEMBL3683266 | 0.79 | NAAA (0.50) | DNM1DGKATHRBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255126-B1 | 2-ACYLOXYPROPYLAMINE DERIVATIVES, METHOD FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0255126-A2 | 2-Acyloxypropylamine derivatives, method for their preparation and medicaments containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |