Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 7/20 | 0.52 |
| ▸ | CA9 | Q16790 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243296 | 0.90 | PKM (0.75) | PKMCA2CA12CA9CA1 | |
| SCHEMBL9646422 | 0.89 | PKM (0.69) | PKMCA2CA12CA9CA1 | |
| SCHEMBL30068292 | 0.88 | PKM (1.00) | PKMCA2CA12CA9CA1 | |
| SCHEMBL8777777 | 0.88 | PKM (1.00) | PKMCA2CA12CA9CA1 | |
| SCHEMBL11688578 | 0.87 | PKM (0.70) | PKMCA2CA12CA9CA1 | |
| SCHEMBL9646206 | 0.86 | PKM (0.60) | PKMCA2CA12CA9CA1 | |
| SCHEMBL8777836 | 0.85 | PKM (0.73) | PKMCA2CA12CA9CA1 | |
| SCHEMBL3782589 | 0.83 | PKM (0.61) | PKMCA2CA12CA9CA1 | |
| SCHEMBL11497077 | 0.83 | PKM (0.71) | PKMCA2CA12CA9CA1 | |
| SCHEMBL9647121 | 0.82 | ALDH1A1 (0.58) | PKMCA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0039306-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-01-11 | — | — | EP | disclosed |
| EP-0039306-A1 | Azo dyestuffs, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |