Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645148 | 0.90 | PKM (0.79) | PKMCA2CA1CA12CA9 | |
| SCHEMBL30068292 | 0.86 | PKM (1.00) | PKMCA2CA1CA12CA9 | |
| SCHEMBL8777777 | 0.86 | PKM (1.00) | PKMCA2CA1CA12CA9 | |
| SCHEMBL2777269 | 0.85 | CA12 (0.61) | PKMCA2CA1CA12CA9 | |
| SCHEMBL3782589 | 0.85 | PKM (0.61) | PKMCA2CA1CA12CA9 | |
| SCHEMBL7242421 | 0.85 | PKM (0.61) | PKMCA2CA1CA12CA9 | |
| SCHEMBL17774552 | 0.82 | CA2 (0.65) | PKMCA2CA1CA12CA9 | |
| SCHEMBL2914715 | 0.82 | PKM (0.56) | PKMCA2CA1KDM4EALDH1A1 | |
| SCHEMBL9646206 | 0.81 | PKM (0.60) | PKMCA2CA1CA12CA9 | |
| SCHEMBL10721933 | 0.81 | PKM (0.56) | PKMCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147494-C | Novel benzodiazine compound, its preparation method and medicine composition containing them | ɪά��ʵ���� | 2004-04-28 | — | — | CN | disclosed |
| US-6635635-B2 | 5,5-dioxo-2,3,3a,4-tetrahydro-1 H-pyrrolo(2,1-c)(1,2,4)-benzothiadiazin-7-ol, for example; nervous system disorders; alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) modulators | LES LABORATOIRES SERVIER (FR) | 2003-10-21 | — | — | US | disclosed |
| US-20020037894-A1 | Benzothiadiazine compounds | ADIR ET COMPAGNIE (FR) | 2002-03-28 | — | — | US | disclosed |
| CN-1341599-A | Novel benzodiazine compound, its preparation method and medicine composition containing them | LAB SEUWILL (FR) | 2002-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037894-A1 | Benzothiadiazine compounds | HCAR1, GLRA1, HCAR2 | PKM 2104/4885CA2 1488/4885CA1 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.