Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685387 | 0.84 | TDP1 (0.37) | TDP1ALDH1A1TP53GLACYP3A4 | |
| SCHEMBL18289495 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1TP53NT5ESMN1; SMN2 | |
| SCHEMBL1808650 | 0.78 | ALDH1A1 (0.40) | TDP1ALDH1A1TP53GLACYP3A4 | |
| SCHEMBL167674 | 0.76 | SLC9A1 (0.37) | TDP1ALDH1A1TP53GLACYP3A4 | |
| SCHEMBL28115708 | 0.75 | SLC9A1 (0.36) | TDP1ALDH1A1TP53GLACYP3A4 | |
| SCHEMBL11764661 | 0.75 | BRD4 (0.41) | TDP1ALDH1A1TP53GAAHPGD | |
| SCHEMBL19194608 | 0.75 | TRPA1 (0.38) | TDP1ALDH1A1TP53GLACYP3A4 | |
| SCHEMBL18074247 | 0.75 | POLB (0.41) | GLAGAAPTGS1PTGS2ELANE | |
| SCHEMBL3199219 | 0.74 | TDP1 (0.38) | TDP1 | |
| SCHEMBL1355486 | 0.72 | TDP1 (0.43) | TDP1ALDH1A1SMN1; SMN2HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539659-B1 | ION EXCHANGE CHROMATOGRAPHY COLUMN, METHOD, AND SYSTEM THEREOF | DIONEX CORP (US) | 2022-12-07 | — | — | EP | claimed |
| EP-0293740-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED LACTAMS | BASF Aktiengesellschaft (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0293740-A2 | Process for the preparation of substituted lactams | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |