Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647127 | 0.80 | ALOX5 (0.53) | ALOX5NAMPTALDH1A1LMNAKDM4E | |
| SCHEMBL9669683 | 0.80 | ALOX5 (0.54) | ALOX5NAMPTALDH1A1CYP3A4KDM4E | |
| SCHEMBL9646389 | 0.74 | ALOX5 (0.70) | ALOX5KMT2AMEN1CYP3A4PKM | |
| SCHEMBL916112 | 0.74 | NAMPT (0.48) | NAMPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9596545 | 0.72 | ALOX5 (1.00) | ALOX5KDM4EPKM | |
| SCHEMBL17790711 | 0.70 | PARP1 (0.53) | NAMPTKMT2AMEN1CYP17A1CYP3A4 | |
| SCHEMBL29457342 | 0.69 | NAMPT (0.80) | NAMPTLMNAHTTCYP3A4KDM4E | |
| SCHEMBL349933 | 0.69 | NAMPT (0.80) | NAMPTLMNAHTTCYP3A4KDM4E | |
| SCHEMBL25468287 | 0.68 | NAMPT (0.40) | NAMPTMAPTCYP17A1CYP3A4GAA | |
| SCHEMBL5716528 | 0.67 | CYP3A4 (0.44) | NAMPTALDH1A1CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |