Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989338 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HDAC3HDAC1CYP1A2CYP2C9 | |
| SCHEMBL26414586 | 0.73 | CYP3A4 (0.58) | CYP3A4NAMPTRAB9ACYP1A2CYP2C9 | |
| SCHEMBL9669683 | 0.72 | ALOX5 (0.54) | CYP3A4ALDH1A1PKMNAMPTRAB9A | |
| SCHEMBL9439389 | 0.71 | CYP3A4 (0.59) | CYP3A4ALDH1A1PKMNAMPTRAB9A | |
| SCHEMBL5716532 | 0.71 | ALDH1A1 (0.46) | CYP3A4ALDH1A1PKMSLC16A3CYP1A2 | |
| SCHEMBL479925 | 0.71 | CYP3A4 (0.72) | CYP3A4ALDH1A1PKMNAMPTCYP1A2 | |
| SCHEMBL10235975 | 0.70 | NAMPT (0.47) | CYP3A4PKMNAMPTRAB9A | |
| SCHEMBL2413941 | 0.70 | NAMPT (0.51) | CYP3A4NAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL13989341 | 0.70 | ALDH1A1 (0.64) | ALDH1A1PKMCYP1A2 | |
| SCHEMBL30546609 | 0.70 | NAMPT (0.46) | CYP3A4NAMPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462204-B2 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | WELLA AG (DE) | 2008-12-09 | — | — | US | disclosed |
| US-7462204-B2 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | WELLA AG (DE) | 2008-12-09 | — | — | US | disclosed |
| US-20070056120-A1 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2007-03-15 | — | — | US | disclosed |
| US-20070056120-A1 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2007-03-15 | — | — | US | disclosed |
| EP-1687280-A1 | CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051918-A1 | CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070056120-A1 | Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds | KRT18, DSP, TUBA4A | CYP3A4 1583/4885ALDH1A1 978/4885PKM 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.