Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651588 | 0.84 | PTPN1 (0.48) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL997660 | 0.81 | MAPT (0.49) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL1545562 | 0.79 | PKM (0.52) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL4476255 | 0.79 | CA12 (0.57) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL27907766 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL2991009 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL30389755 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL11884043 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL28278468 | 0.77 | MAPT (0.51) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL27883272 | 0.77 | ATM (0.42) | ALDH1A1HPGDHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143675-C | Heteroarylpiperidines, pyrrolidines and piprazines and their use as antipsychotics and analgetics | ���µ�˹ҩ�﹫˾ | 2004-03-31 | — | — | CN | disclosed |
| CN-1136275-A | Arylheterocyclylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics | HOECHST ROUSSEL PHARMA (US) | 1996-11-20 | — | — | CN | disclosed |
| US-5113019-A | PROCESS FOR PHENOL ALKYLTHIOLATION AND ITS APPLICATION TO THE SYNTHESIS OF 4-ACYL-2-ALKYLTHIOPHENOLS | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1992-05-12 | — | — | US | disclosed |
| US-4751246-A | ALPHA(AMINOALKYL)-4-HYDROXY-3-(ALKYLSULFINYL) BENZENEMETHANOL AND 2-(4-HYDROXY-3-(ALKYLSULFINYL) PHENYL)ETHYLAMINE-HYPOTENSIVE AGENTS | STERLING DRUG INC. (US) | 1988-06-14 | — | — | US | disclosed |
| US-4695589-A | HYPOTENSIVE AGENTS | STERLING DRUG INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4452816-A | HYPOTENSIVE AND ANTIARRHYTHMIA AGENTS | STERLING DRUG INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4374149-A | HYPOTENSIVE AGENT AND VASODILATOR | STERLING DRUG INC. (US) | 1983-02-15 | — | — | US | disclosed |