SCHEMBL1435520

SCHEMBL1435520

CCc1nc(C)cn1CCCN

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.41
TSHR P16473 4/20 0.34
CYP1A2 P05177 1/20 0.34
LMNA P02545 3/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 2/20 0.33
TLR8 Q9NR97 5/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
CSNK2A3 Q8NEV1 1/20 0.32
SPNS2 Q8IVW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27867261 0.95 CYP19A1 (0.40) CYP19A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL585669 0.89 CYP19A1 (0.43) CYP19A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL14305754 0.85 CYP19A1 (0.43) CYP19A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL27850120 0.85 CYP19A1 (0.45) CYP19A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL3868934 0.82 SPNS2 (0.49) TSHRLMNAMAPTTLR8SPNS2
SCHEMBL16268174 0.82 CYP19A1 (0.44) CYP19A1TSHRCYP1A2LMNAHTT
SCHEMBL5691544 0.82 TLR8 (0.42) CYP19A1TLR8ALDH1A1
SCHEMBL5691629 0.82 TLR8 (0.42) CYP19A1TLR8ALDH1A1
SCHEMBL9645498 0.81 CYP19A1 (0.45) CYP19A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL3877612 0.79 CYP1A2 (0.40) TSHRCYP1A2TLR8PIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181377-A Cyclotriphosphazene-based flame-retardant imidazole curing agent and preparation method and application thereof 常州百思通复合材料有限公司 2022-03-15 CN claimed
CN-110016123-B Heat-resistant flame-retardant epoxy resin latent curing agent 广东固研电子材料有限公司 2021-07-09 CN claimed
CN-110016123-A A kind of heat-resisting flame-retardant epoxy resin lalent solidifying agent 广州市固研电子材料有限公司 2019-07-16 CN claimed
US-7479527-B2 Polyepoxide and reaction product of aminoalkylimidazole, polyamine, urea and diepoxide as curing component FUJI KASEI KOGYO CO., LTD. (JP) 2009-01-20 US claimed
US-20080033116-A1 One-Component Heat Curable Epoxide Composition FUJI KASEI KOGYO, CO., LTD. (JP) 2008-02-07 US claimed
EP-0677540-B1 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AG (DE) 1999-01-27 EP claimed
US-5786402-A PRODUCING FLEXIBLE FOAM WITH REDUCED ODOR AND REDUCED FOGGING VALUE BASF AKTIENGESELLSCHAFT (DE) 1998-07-28 US claimed
EP-0677540-A2 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AKTIENGESELLSCHAFT (DE) 1995-10-18 EP claimed
JP-1146871-A None JP disclosed
JP-1066172-A None JP disclosed
EP-4747320-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-05-27 EP disclosed
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION HENKEL AG & CO KGAA (DE) 2026-05-21 US disclosed
EP-4526365-A1 ACRYLATE-EPOXY RESIN COMPOSITIONS Lyondellbasell Composites LLC (US) 2025-03-26 EP disclosed
WO-2025015542-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION HENKEL AG & CO. KGAA (DE) 2025-01-23 WO disclosed
JP-H01146871-A AMINOPROPYLIMIDAZOLE W R GRACE & CO 1989-06-08 JP disclosed
EP-0188999-B1 CATIONIC REACTION PRODUCTS FROM 1-AMINOALKYL IMIDAZOLE COMPOUNDS AND EPIHALOGEN HYDRINS CIBA-GEIGY AG (CH) 1989-05-31 EP disclosed
US-4816589-A Aminopropylimidazoles W. R. GRACE & CO.-CONN. (US) 1989-03-28 US disclosed
US-4797455-A Isocyanates blocked with 1-amino-alkyl imidazoles as epoxy curing agents W. R. GRACE & CO.-CONN. (US) 1989-01-10 US disclosed
US-4705865-A Cationic reaction products formed from 1-aminoalkyl-imidazole compounds and epihalohydrins CIBA-GEIGY CORPORATION (US) 1987-11-10 US disclosed
EP-0188999-A1 Cationic reaction products from 1-aminoalkyl imidazole compounds and epihalogen hydrins CIBA-GEIGY AG (CH) 1986-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION MAT1A, MAT2B, MAT2A CYP19A1 4020/4885TSHR 2841/4885CYP1A2 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.