Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647591 | 0.89 | CCNE2 (0.40) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL10401911 | 0.87 | CCNB2 (0.36) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL9647633 | 0.87 | PDE10A (0.39) | MEN1KMT2APDE10APARP1KDM4E | |
| Hydrochloric Acid SCHEMBL10401640 | 0.86 | PDE10A (0.38) | MEN1KMT2APDE10APARP1KDM4E | |
| SCHEMBL4759339 | 0.80 | PARP1 (0.39) | MEN1KMT2AMAPTPARP1ALDH1A1 | |
| Mivazerol SCHEMBL593708 | 0.79 | PARP1 (0.39) | MEN1KMT2AMAPTPDE10APARP1 | |
| Mivazerol SCHEMBL8097939 | 0.79 | PARP1 (0.39) | MEN1KMT2AMAPTPDE10APARP1 | |
| Mivazerol SCHEMBL8865135 | 0.78 | PARP1 (0.38) | MEN1KMT2AMAPTPDE10APARP1 | |
| SCHEMBL9648172 | 0.76 | MRGPRX4 (0.48) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10401901 | 0.75 | ALDH1A1 (0.38) | KMT2ALMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |