SCHEMBL2170993

SCHEMBL2170993

CC(=O)Oc1ccc(N(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
MAPT P10636 6/20 0.56
ALDH1A1 P00352 6/20 0.56
HPGD P15428 2/20 0.56
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
ELANE P08246 1/20 0.52
RAB9A P51151 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GFER P55789 2/20 0.50
THRB P10828 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
TP53 P04637 2/20 0.49
ESR2 Q92731 1/20 0.49
NOX1 Q9Y5S8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22355275 0.89 NPC1 (0.62) LMNAMAPTALDH1A1HPGDPOLB
SCHEMBL11841636 0.87 MAPT (0.56) LMNAMAPTALDH1A1HPGDPOLB
Hydrochloric Acid SCHEMBL11841634 0.85 MAPT (0.54) LMNAMAPTALDH1A1HPGDPOLB
SCHEMBL11193145 0.85 ALDH1A1 (0.46) LMNAMAPTALDH1A1HPGDPOLB
SCHEMBL8970607 0.83 SMN1; SMN2 (0.57) LMNAMAPTALDH1A1POLBPKM
SCHEMBL269329 0.83 LMNA (0.80) LMNAMAPTALDH1A1POLBPKM
SCHEMBL472273 0.83 MAPT (0.47) LMNAMAPTALDH1A1HPGDRAB9A
SCHEMBL463663 0.83 LMNA (0.59) LMNAMAPTALDH1A1POLBPKM
SCHEMBL12573304 0.82 ALDH1A1 (0.66) LMNAMAPTALDH1A1HPGDPKM
SCHEMBL4680703 0.82 ELANE (0.61) LMNAMAPTALDH1A1HPGDELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111777520-B Synthesis method of multi-substituted dimethylamino phenyl acetic acid compound 苏州爱玛特生物科技有限公司 2023-04-07 CN claimed
CN-101654396-B Conversion of a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin DOW GLOBAL TECHNOLOGIES INC US 2014-09-24 CN claimed
CN-101654396-A Conversion of a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin DOW GLOBAL TECHNOLOGIES INC US 2010-02-24 CN claimed
CN-1976886-A Conversion of multihydroxylated-aliphatic hydrocarbon or ester thereof to chlorohydrin DOW GLOBAL TECHNOLOGIES INC (US) 2007-06-06 CN claimed
CN-102753519-A Diacylated hydroxylamine derivatives UNIV JOHNS HOPKINS 2012-10-24 CN disclosed
CN-102653158-A Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP 2012-09-05 CN disclosed
CN-102529310-A Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP 2012-07-04 CN disclosed
CN-101400657-B Polycyclic cinnamamide derivative ESAI R & D MAN CO LTD 2012-05-30 CN disclosed
CN-102459268-A Diazahomoadamantane derivatives and methods of use thereof ABBOTT LAB 2012-05-16 CN disclosed
EP-2346865-A1 INDOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS Merck Frosst Canada Ltd. (CA) 2011-07-27 EP disclosed
CN-102129172-A Negative resist composition and patterning process SHINETSU CHEMICAL CO 2011-07-20 CN disclosed
US-7956020-B2 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
WO-1998004542-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-05 WO disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed