Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183449 | 0.81 | ALOX5 (0.55) | ALOX5CHRNB2CHRNA4HTR3A | |
| SCHEMBL3783753 | 0.79 | CHRNB2 (0.53) | CHRNB2CHRNA4HTR3A | |
| SCHEMBL11193669 | 0.76 | HTR3A (0.51) | CHRNB2CHRNA4HTR3A | |
| SCHEMBL6009938 | 0.74 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL4355823 | 0.71 | CHRNB2 (0.89) | CHRNB2CHRNA4HTR3A | |
| SCHEMBL30020071 | 0.71 | CHRNB2 (0.89) | CHRNB2CHRNA4HTR3A | |
| Hydrochloric Acid SCHEMBL4057198 | 0.70 | CHRNB2 (0.86) | CHRNB2CHRNA4HTR3A | |
| SCHEMBL9645440 | 0.69 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9645242 | 0.69 | CRBN (0.52) | ALOX5 | |
| SCHEMBL9645660 | 0.69 | CYP11B1 (0.43) | CHRNB2CHRNA4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |