Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645791 | 0.71 | ALOX5 (0.42) | ELANEALOX5MGLLMAPTALDH1A1 | |
| SCHEMBL9645705 | 0.63 | ALOX5 (0.46) | ALOX5MAPTALDH1A1MAPK1HSD17B10 | |
| SCHEMBL28353519 | 0.63 | F2 (0.35) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL13798745 | 0.60 | ADRB1 (0.45) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL19214040 | 0.59 | ELANE (1.00) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL11734241 | 0.59 | GSK3A (0.57) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL12613234 | 0.59 | GSK3A (0.57) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL10361315 | 0.59 | F2 (0.35) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL5328006 | 0.59 | GSK3A (0.60) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL28357023 | 0.59 | F2 (0.39) | ELANEF2CTSGCMA1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |