Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644889 | 0.83 | TDP1 (0.48) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11674110 | 0.80 | HPGD (0.47) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL8894140 | 0.79 | TDP1 (0.44) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11674473 | 0.79 | TDP1 (0.44) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL988047 | 0.77 | TGM2 (0.44) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11674767 | 0.77 | TDP1 (0.42) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL305727 | 0.77 | ALDH1A1 (0.45) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL22089888 | 0.76 | CA12 (0.39) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL10993427 | 0.76 | GAA (0.49) | TDP1GAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11673040 | 0.76 | GAA (0.41) | TDP1GAASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000030-B1 | DIURETHANES CONTAINING SULPHUR, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | claimed |
| EP-0000030-A1 | Diurethanes containing sulphur, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1978-12-20 | — | — | EP | claimed |
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |