SCHEMBL305727

SCHEMBL305727

C=C(C)C(=O)OC(C)Nc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RXFP1 Q9HBX9 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ELANE P08246 1/20 0.41
HSD17B10 Q99714 3/20 0.40
NAPRT Q6XQN6 1/20 0.40
TSHR P16473 3/20 0.38
LMNA P02545 3/20 0.38
CYP3A4 P08684 2/20 0.38
ATM Q13315 2/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
RECQL P46063 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 1/20 0.38
KLK7 P49862 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644889 0.82 TDP1 (0.48) ALDH1A1GAASMN1; SMN2RXFP1TDP1
SCHEMBL12310351 0.81 HSD17B10 (0.53) SMN1; SMN2HSD17B10NAPRTTSHRMAPT
SCHEMBL8440014 0.80 HPGD (0.45) ALDH1A1KDM4EGAASMN1; SMN2TDP1
SCHEMBL7639474 0.78 ALDH1A1 (0.45) ALDH1A1KDM4EGAASMN1; SMN2RXFP1
SCHEMBL6569464 0.78 MAPT (0.44) ALDH1A1KDM4EGAASMN1; SMN2ELANE
SCHEMBL6569467 0.78 TSHR (0.51) ALDH1A1KDM4EGAASMN1; SMN2RXFP1
SCHEMBL28334967 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EGAASMN1; SMN2RXFP1
SCHEMBL9645668 0.77 TDP1 (0.47) ALDH1A1GAASMN1; SMN2RXFP1TDP1
SCHEMBL988047 0.77 TGM2 (0.44) ALDH1A1GAASMN1; SMN2RXFP1TDP1
SCHEMBL2951343 0.76 NAPRT (0.44) ALDH1A1KDM4EGAASMN1; SMN2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1970614-B Thermoplastic resin composition TORAY FIBER RES INST CN CO LTD 2012-04-04 CN claimed
JP-2011518236-A 2011-06-23 JP claimed
US-20110111350-A1 Conjugated Polymers CRANFIELD UNIVERSITY (GB) 2011-05-12 US claimed
EP-2269194-A1 CONJUGATED INTERPENETRATED POLYMERIC NETWORKS Cranfield University (GB) 2011-01-05 EP claimed
WO-2009118525-A1 CONJUGATED INTERPENETRATED POLYMERIC NETWORKS CRANFIELD UNIVERSITY (GB) 2009-10-01 WO claimed
CN-1970614-A Thermoplastic resin composition TORAY FIBER RES INST CN CO LTD (CN) 2007-05-30 CN claimed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US claimed
US-6765713-B2 STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT RICOH COMPANY, LTD. (JP) 2004-07-20 US claimed
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) 2003-12-18 US claimed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP claimed
WO-1995030646-A1 COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS VANGUARD MEDICA LIMITED (GB) 1995-11-16 WO claimed
EP-0370753-B1 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL IND (JP) 1995-01-18 EP claimed
EP-0507561-A1 Thermoplastic resin compositions NOF CORPORATION (JP) 1992-10-07 EP claimed
CN-1043144-A Modified polyolefin particles and preparation method thereof MITSUI PETROCHEMICAL IND (JP) 1990-06-20 CN claimed
EP-0370753-A2 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-05-30 EP claimed
EP-0335676-A2 Developer for developing electrostatic image and image forming method CANON KABUSHIKI KAISHA (JP) 1989-10-04 EP claimed
US-20260022243-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO UMG CO LTD (JP) 2026-01-22 US disclosed
EP-4682182-A1 GRAFT-MODIFIED ETHYLENE/1-BUTENE COPOLYMER, POLYAMIDE RESIN COMPOSITION, AND MOLDED BODY Mitsui Chemicals, Inc. (JP) 2026-01-21 EP disclosed
US-4503140-A Radiation-sensitive compositions of polymers containing a π-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-05 US disclosed
EP-0095269-A2 Radiation-sensitive compositions of polymers containing a pi-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022243-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE VMA21, VCP, VMP1 ALDH1A1 1858/4885KDM4E 1296/4885GAA 636/4885
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device NEFM, ERGIC1, VCL ALDH1A1 1448/4885KDM4E 4856/4885GAA 3473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.