Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646680 | 0.89 | NPC1 (0.52) | NPC1GRIN1GRIN2BALDH1A1KDM4E | |
| SCHEMBL12124539 | 0.87 | NPC1 (0.69) | NPC1HTR1A | |
| SCHEMBL9646137 | 0.87 | HTR1A (0.60) | ALDH1A1KDM4EHTR1A | |
| SCHEMBL9644860 | 0.87 | KDM4E (0.49) | ALDH1A1KDM4EHTR1A | |
| SCHEMBL9644844 | 0.84 | TSHR (0.51) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL9592125 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4E | |
| SCHEMBL9592310 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4E | |
| SCHEMBL9646151 | 0.83 | HTR7 (0.52) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL9589962 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4E | |
| SCHEMBL9589251 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | claimed |
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |