Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647603 | 0.90 | ALDH1A1 (0.50) | HTR7ALDH1A1KDM4EADRA1AADRA1B | |
| SCHEMBL9644844 | 0.88 | TSHR (0.51) | HTR7ALDH1A1KDM4EADRA1AADRA1B | |
| SCHEMBL9647687 | 0.86 | HTR1A (0.65) | HTR7ADRA1AHTR1ADRD2DRD3 | |
| SCHEMBL9646137 | 0.84 | HTR1A (0.60) | HTR7ALDH1A1KDM4EHTR1A | |
| SCHEMBL9644860 | 0.84 | KDM4E (0.49) | HTR7ALDH1A1KDM4EHTR1A | |
| SCHEMBL9592125 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4EDRD2 | |
| SCHEMBL9645757 | 0.83 | NPC1 (0.53) | ALDH1A1KDM4EADRA1AADRA1BADRA1D | |
| SCHEMBL9592310 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4E | |
| SCHEMBL9589962 | 0.80 | KDM4E (0.52) | ALDH1A1KDM4E | |
| SCHEMBL9589251 | 0.80 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |