Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 12/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922525 | 0.87 | DPP4 (0.52) | MAPTLMNATP53NOTUMMEN1 | |
| SCHEMBL20080888 | 0.86 | NOTUM (0.58) | MAPTLMNATP53NOTUMMEN1 | |
| SCHEMBL2921346 | 0.84 | DPP4 (0.51) | MAPTLMNATP53NOTUMMEN1 | |
| SCHEMBL8320138 | 0.82 | SIRT6 (0.59) | NOTUMMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1254422 | 0.82 | MAPT (0.57) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28809856 | 0.81 | SLC6A2 (0.49) | MAPTLMNAKMT2ASMN1; SMN2SLC6A2 | |
| SCHEMBL8320134 | 0.79 | NOTUM (0.52) | MAPTLMNATP53NOTUMMEN1 | |
| SCHEMBL5183526 | 0.77 | HSD17B10 (0.45) | MAPTLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16672426 | 0.77 | SLC6A2 (0.56) | SLC6A2SLC6A4 | |
| SCHEMBL3243736 | 0.77 | NOTUM (0.53) | MAPTLMNATP53NOTUMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |