Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646339 | 0.84 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9646895 | 0.82 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9646598 | 0.81 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9645952 | 0.81 | ALOX5 (0.70) | ALOX5KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9647813 | 0.79 | ADAM17 (0.55) | ALOX5KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9646320 | 0.75 | ALOX5 (0.51) | ALOX5ALDH1A1 | |
| SCHEMBL9646981 | 0.71 | ALOX5 (0.66) | ALOX5KDM4EALDH1A1HPGD | |
| SCHEMBL1069838 | 0.70 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9646928 | 0.70 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL18149885 | 0.70 | NPSR1 (0.49) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |