Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412933 | 0.87 | ACHE (0.43) | ACHEALDH1A1L3MBTL1CYP3A4CRHR1 | |
| SCHEMBL18509209 | 0.85 | ACHE (0.52) | ACHEALDH1A1L3MBTL1CYP3A4CRHR1 | |
| SCHEMBL11469036 | 0.84 | TSHR (0.51) | ACHEALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12046935 | 0.83 | ACHE (0.50) | ACHEALDH1A1L3MBTL1CYP3A4HPGD | |
| SCHEMBL10632613 | 0.83 | MAPT (0.51) | ALDH1A1L3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL9513866 | 0.81 | CA12 (0.52) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL11318955 | 0.81 | HPGD (0.45) | ACHEALDH1A1L3MBTL1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL11451996 | 0.81 | ACHE (0.41) | ACHEALDH1A1L3MBTL1CYP3A4CRHR1 | |
| SCHEMBL9619800 | 0.80 | ACHE (0.47) | ACHEALDH1A1L3MBTL1CYP3A4HPGD | |
| SCHEMBL24384023 | 0.79 | ALDH1A1 (0.46) | ACHEALDH1A1L3MBTL1CRHR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090284-A1 | EUROPIUM(III) COMPLEXES AS PH SENSORS | CISBIO BIOASSAYS (FR) | 2022-05-05 | — | — | WO | disclosed |
| EP-3992182-A1 | EUROPIUM(III) COMPLEXES AS PH SENSORS | Cisbio Bioassays (FR) | 2022-05-04 | — | — | EP | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4760183-A | Process for the preparation of aromatic dialkylamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| US-4689050-A | Mixtures of blue disperse azo dyestuffs for dyeing synthetic fibers | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4602084-A | Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component | CIBA-GEIGY CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0147783-A2 | Mixtures of blue disperse azo dyes for the dyeing of synthetic fibres | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-10 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| US-4212642-A | MONOAZO DYES | CIBA-GEIGY AG (CH) | 1980-07-15 | — | — | US | disclosed |
| US-4134887-A | FIBER-REACTIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4066638-A | WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
| US-4036825-A | DYES FOR CELLULOSE OR NITROGEN-CONTAINING FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342031-A1 | QUENCHER | AHR, GFER, AKR1A1 | ACHE 2853/4885ALDH1A1 365/4885L3MBTL1 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.